Published Research

Published Research Related to SUDC

  • Gould Crandall, L. Inexplicable Child Deaths: Medicolegal Death Investigation Resources From the SUDC Foundation and the SUDC Registry and Research Collaborative  Acad Forensic Pathol. 2017 7(2): xxiv-xxvii
  • Gould Crandall L, Reno L, Himes B, Robinson D. The Diagnostic Shift of SIDS to Undetermined: Are There Unintended Consequences? Acad Forensic Pathol. 2017 7(2): 212-220
  • Ackerman MJ1, Andrew TA2, Baker AM3, Devinsky O4, Downs JC5, Keens T6, Kuntz J7, Lin P1, Lear-Kaul KC8, Reichard R1, Robinson DA9. An Association of Hippocampal Malformations and Sudden Death? We Need More Data.Forensic Sci Med Pathol. 2016 Jun;12(2):229-31. doi: 10.1007/s12024-016-9765-1. Epub 2016 Mar 26.
  • Halvorsen M, Petrovski S, Shellhaas R, Tang Y, Crandall L, Goldstein D, Devinsky O.  Mosaic mutations in early-onset genetic diseases Genet Med. 2016 Jul;18(7):746-9. doi: 10.1038/gim.2015.155. Epub 2015 Dec 30. PMID: 26716362 Free PMC Article available
  • Hefti MM, Cryan JB, Haas EA, Chadwick AE, Crandall LA, Trachtenberg FL, Armstrong DD, Grafe M, Krous HF, Kinney HC.  Hippocampal malformation associated with sudden death in early childhood: a neuropathologic study: Part 2 of the investigations of The San Diego SUDC Research Project, Forensic Sci Med Pathol. 2016 Mar;12(1):14-25. doi: 10.1007/s12024-015-9731-3. Epub 2016 Jan 19. PMID: 26782962
  • Hefti MM, Kinney HC, Cryan JB, Haas EA, Chadwick AE, Crandall LA, Trachtenberg FL, Armstrong DD, Grafe M, Krous HF.  Sudden unexpected death in early childhood: general observations in a series of 151 cases: Part 1 of the investigations of the San Diego SUDC Research Project Forensic Sci Med Pathol. 2016 Mar;12(1):4-13. doi: 10.1007/s12024-015-9724-2. Epub 2016 Jan 19. PMID: 26782961 Free PMC Article 
  • Bagnall RD, Weintraub RG, Ingles J, Duflou J, Yeates L, Lam L, Davis AM, Thompson T, Connell V, Wallace J, Naylor C, Crawford J, Love DR, Hallam L, White J, Lawrence C, Lynch M, Morgan N, James P, du Sart D, Puranik R, Langlois N, Vohra J, Winship I, Atherton J, McGaughran J, Skinner JR, Semsarian C. N Engl J Med. 2016 Jun 23;374(25):2441-52. doi: 10.1056/NEJMoa1510687. PMID: 27332903
  • Hesdorffer DC, Crandall LA, Friedman D, Devinsky O; Sudden unexplained death in childhood: A comparison of cases with and without a febrile seizure history. Epilepsia. 2015 Aug;56(8):1294-300. doi: 10.1111/epi.13066. Epub 2015 Jun 29
  • Rudd R, Capizzi Marain L, Crandall L To Hold or Not to Hold: Medicolegal Death Investigation Practices During Unexpected Child Death Investigations and the Experiences of Next of Kin. Am J Forensic Med Pathol. 2014 Jun;35(2):132-9
  • Rudd, R. & D’Andrea, L. (2013). Professional support requirements and grief interventions for parents bereaved by an unexplained death at different time periods in the grief process. International Journal of Emergency Mental Health and Human Resilience, 15(1), 51-68.
  • McGarvey C, O'Regan M, Cryan J, Treacy A, Hamilton K, Devaney D and Matthews T. Sudden unexplained death in childhood (1–4 years) in Ireland: an epidemiological profile and comparison with SIDS Arch Dis Child (2012)
  • Ingrid A. Holm MD, MPH, Annapurna Poduri MD, MPH, Laura Crandall PT, MA, Elisabeth Haas MPH, Marjorie R. Grafe MD, PhD, Hannah C. Kinney MD, Henry F. Krous MD, Inheritance of Febrile Seizures in Sudden Unexplained Death in Toddlers. Pediatric Neurology 46 (2012) 235e239
  • Baker AM, Crandall L. To Hold Or Not To Hold. Forensic Sci Med Pathol. 2009 (Dec; 5(4):321-3. Epub 2009 Nov 13. "To Hold Or Not To Hold". You can also obtain the published article by visiting SpringerLink.
  • Hannah C. Kinney, M.D., Amy E. Chadwick, B.A., Laura A. Crandall, M.A., Marjorie Grafe, M.D., Dawna L. Armstrong, M.D., William J. Kupsky, M.D., Felicia L. Trachtenberg, Ph.D., and Henry F. Krous, M.D. Sudden Death, Febrile Seizures, and Hippocampal and Temporal Lobe Maldevelopment in Toddlers: A New Entity Pediatr Dev Pathol 2009 Jul 16:1. Epub 2009 Jul 16
  • Krous HF, Wahl C, Chadwick AE. Sudden unexpected death in a toddler with Williams Syndrome. Forens Sci Med Pathol. In Press.
  • Kinney HC, Armstrong DL, Chadwick AE, et al. Sudden Death in Toddlers Associated with Developmental Abnormalities of the Hippocampus: a report of five cases. Pediatr Dev Pathol. 2007;10:208-223
  • Krous H, Chadwick A, Miller D, Crandall L, Kinney H. Sudden Death in Toddlers with Viral Meningitis, Massive Cerebral Edema, and Neurogenic Pulmonary Edema and Hemorrhage: Report of Two Cases. Pediatr Dev Pathol. 2007;10:463-469
  • Masoumi H, Kinney HC, Chadwick AE, Rubio A, Krous HF. Sudden unexpected death in childhood associated with cardiac rhabdomyoma, involuting adrenal ganglioneuroma, and megalencephaly: another expression of tuberous sclerosis? Pediatr Dev Pathol. 2007;10:129-133.
  • Krous HF, Chadwick AE, Crandall L, Nadeau-Manning. Sudden Unexpected Death In Childhood: A Report of 50 Cases. Pediatric Dev Pathol. 2005;8:307-319
  • Wixom C, Krous HF, Chadwick AE. Sudden, Unexpected Death Associated with Meningioangiomatosis. Pediatr Dev Pathol. 2005;8:240-244
  • Kinney H, Armstrong DL, Chadwick AE, Crandall L, Hilbert C, Krous H. Abstract: Seizures, Cerebral Edema and Hippocampal Anomolies in Sudden Unexplained Death In Childhood (SUDC): Report of A Series. J Neuropathol Exp Neurology 2004; 63 (5):556
  • Beckwith JB. The sudden infant death syndrome. Curr Probl Pediatr 1973;3(8):1-36.
  • Southall DP, Stebbens V, Shinebourne EA. Sudden and unexpected death between 1 and 5 years. Arch Dis Child 1987;62(7):700-5.
  • Helweg-Larsen K, Garde E. Sudden natural death in childhood. A review of forensic autopsy protocols in cases of sudden death between the ages of one and five years, 1982-1991, with a special view to sudden unexplained death. Acta Paediatr 1993;82(11):975-8.
  • Molander N. Sudden natural death in later childhood and adolescence. Arch Dis Child 1982;57(8):572-6.
  • Neuspiel DR, Kuller LH. Sudden and unexpected natural death in childhood and adolescence. Jama 1985;254(10):1321-5.
  • Siboni A, Simonsen J. Sudden unexpected natural death in young persons. Forensic Sci Int 1986;31(3):159-66.
  • Keeling JW, Knowles SA. Sudden death in childhood and adolescence. J Pathol 1989;159(3):221-4.
  • Norman MG, Taylor GP, Clarke LA. Sudden, unexpected, natural death in childhood. Pediatr Pathol 1990;10(5):769-84.
  • Morentin B, Aguilera B, Garamendi PM, Suarez-Mier MP. Sudden unexpected non-violent death between 1 and 19 years in north Spain. Arch Dis Child. 2000 Jun;82(6):456-61.


References for Channelopathies

  • Ackerman MJ, Tester DJ, Driscoll, DJ. Molecular autopsy of sudden unexplained death in the young. The American Journal of Forensic Medicine and Pathology. 2001; 22(2): 105-111.
  • Ackerman MJ, Khosiseth A, Tester DJ, Hejlik J, Shen WK, Porter CJ. Epinephrine-induced QT interval prolongation: a gene-specific paradoxical response in congenital long QT syndrome. Mayo Clinic Proceedings. 2002;77:413-421.
  • Baruteau AE, Baruteau J, Joomye R, Martins R, Treguer F, Baruteau R,Daubert JC, Mabo P, Roussey M Role of congenital long-QT syndrome in unexplained sudden infant death: proposal for an electrocardiographic screening in relatives Eur J Pediatr. 2009 Mar 6 [Epub ahead of print]


References for metabolic disease and evaluation

  • Rinaldo P, Matern D, Bennett MJ. Fatty acid oxidation disorders. Ann Rev Physiol 64:16.1-26, 2002.
  • Bennett MJ, Rinaldo P. The Metabolic Autopsy comes of Age. Clinical Chemistry 47; 1145-6, 2001.
  • Rinaldo P, Yoon HR, Yu C, Raymond K, Tiozzo C, Giordano G. (1999) Sudden and unexpected neonatal death: A protocol for the postmortem diagnosis of fatty acid oxidation disorders. Sem Perinatol 23:204-210.